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Obesity

CreatedDecember 28, 2020

Last UpdateFebruary 13, 2021

Ross Hanrahan

Drug Dose Calculation in Obesity

Suggested initial doing for commonly used anaesthetic drugs in healthy obese adults ¹

Medication Dosing in Obesity
Dose by Lean Body Weight	Dose by Adjusted Body Weight
Propofol induction Thiopentone Fentanyl Alfentanil Morphine Non-depolarising NMBs Local anaesthetics Paracetamol	Propofol infusion Antibiotics Neostigmine (max 5mg) Sugammadex Suxamethonium LMWH (titrate dose with Xa levels)

Medication Dosing in Obesity
Dose by Lean Body Weight	Propofol induction Thiopentone Fentanyl Alfentanil Morphine Non-depolarising NMBs Local anaesthetics Paracetamol
Dose by Adjusted Body Weight	Propofol infusion Antibiotics Neostigmine (max 5mg) Sugammadex Suxamethonium LMWH (titrate dose with Xa levels)

Enoxaparin Dosing in Obesity

Enoxaparin Thromboprophylaxis Dosing in Obesity²
Weight	< 50kg	50 - 100kg	100 - 150kg	> 150kg
Dose	20mg daily	40mg daily	40mg BD	60mg BD

Enoxaparin Thromboprophylaxis Dosing in Obesity³
Weight	Dose
< 50kg	20mg daily
50 - 100kg	40mg daily
100 - 150kg	40mg BD
> 150kg	60mg BD

Adjusted Body Weight Calculation

References

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